dc.contributor.author | West, Dirk | de |
dc.contributor.author | Claes, Stephan | de |
dc.contributor.author | Deboutte, Dirk | de |
dc.date.accessioned | 2010-11-11T03:35:00Z | de |
dc.date.accessioned | 2012-08-29T23:04:19Z | |
dc.date.available | 2012-08-29T23:04:19Z | |
dc.date.issued | 2009 | de |
dc.identifier.uri | http://www.ssoar.info/ssoar/handle/document/20268 | |
dc.description.abstract | Some evidence suggests that the HPA axis may be dysfunctional in children with attention-deficit/ hyperactivity disorder (ADHD). The aim of this study was to investigate whether a different pattern of HPA axis activity is found between the inattentive (I) and combined (C) subtypes of ADHD, in comparison with healthy control children. A total of 100 prepubertal subjects [52 children with ADHD combined type (ADHD-C), 23 children with ADHD predominantly inattentive type (ADHD-I), and 25 healthy control subjects] were studied. The effects of stress were studied by comparing cortisol responses to a psychosocial stressor, consisting of a public speaking task. Children with ADHD-I showed an elevated cortisol response to the psychosocial stressor, in contrast to children with ADHD-C who showed a blunted cortisol response to the psychosocial stressor. When a distinction was made between responders and non-responders (a subject was classified as a responder when there was an increase in cortisol reactivity), hyperactivity symptoms were clearly related to a lower cortisol reactivity to stress. The results indicate that a low-cortisol responsivity to stress may be a neurobiological marker for children with ADHD-C, but not for those with ADHD-I. Directions for future research and clinical implications are discussed. | en |
dc.language | en | de |
dc.subject.ddc | Psychology | en |
dc.subject.ddc | Psychologie | de |
dc.subject.other | ADHD; Children; Cortisol; HPA axis | |
dc.title | Differences in hypothalamic–pituitary–adrenal axis functioning among children with ADHD predominantly inattentive and combined types | en |
dc.description.review | begutachtet (peer reviewed) | de |
dc.description.review | peer reviewed | en |
dc.source.journal | European Child & Adolescent Psychiatry | de |
dc.source.volume | 18 | de |
dc.publisher.country | DEU | |
dc.source.issue | 9 | de |
dc.subject.classoz | Psychological Disorders, Mental Health Treatment and Prevention | en |
dc.subject.classoz | psychische Störungen, Behandlung und Prävention | de |
dc.subject.thesoz | Stress | de |
dc.subject.thesoz | psychophysical stress | en |
dc.identifier.urn | urn:nbn:de:0168-ssoar-202684 | de |
dc.date.modified | 2010-11-15T13:48:00Z | de |
dc.rights.licence | PEER Licence Agreement (applicable only to documents from PEER project) | de |
dc.rights.licence | PEER Licence Agreement (applicable only to documents from PEER project) | en |
ssoar.gesis.collection | SOLIS;ADIS | de |
ssoar.contributor.institution | http://www.peerproject.eu/ | de |
internal.status | 3 | de |
internal.identifier.thesoz | 10036144 | |
dc.type.stock | article | de |
dc.type.document | journal article | en |
dc.type.document | Zeitschriftenartikel | de |
dc.rights.copyright | f | de |
dc.source.pageinfo | 543-553 | |
internal.identifier.classoz | 10708 | |
internal.identifier.journal | 111 | de |
internal.identifier.document | 32 | |
internal.identifier.ddc | 150 | |
dc.identifier.doi | https://doi.org/10.1007/s00787-009-0011-1 | de |
dc.description.pubstatus | Postprint | en |
dc.description.pubstatus | Postprint | de |
internal.identifier.licence | 7 | |
internal.identifier.pubstatus | 2 | |
internal.identifier.review | 1 | |
internal.check.abstractlanguageharmonizer | CERTAIN | |
internal.check.languageharmonizer | CERTAIN_RETAINED | |