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Genetics of developmental dyslexia

[journal article]

Scerri, Thomas S.
Schulte-Körne, Gerd

Abstract

Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in school-aged children. Linkage studies have identified numerous loci throughout the genome that are likely to harbour candidate dyslexia susceptibility genes. Association studies and the refinement of chromosoma... view more

Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in school-aged children. Linkage studies have identified numerous loci throughout the genome that are likely to harbour candidate dyslexia susceptibility genes. Association studies and the refinement of chromosomal translocation break points in individuals with dyslexia have resulted in the discovery of candidate genes at some of these loci. A key function of many of these genes is their involvement in neuronal migration. This complements anatomical abnormalities discovered in dyslexic brains, such as ectopias, that may be the result of irregular neuronal migration.... view less

Classification
General Psychology
Psychological Disorders, Mental Health Treatment and Prevention

Free Keywords
Developmental dyslexia; Genetics; Reading; Spelling

Document language
English

Publication Year
2009

Page/Pages
p. 179-197

Journal
European Child & Adolescent Psychiatry, 19 (2009) 3

DOI
https://doi.org/10.1007/s00787-009-0081-0

Status
Postprint; peer reviewed

Licence
PEER Licence Agreement (applicable only to documents from PEER project)


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© 2007 - 2025 Social Science Open Access Repository (SSOAR).
Based on DSpace, Copyright (c) 2002-2022, DuraSpace. All rights reserved.