Genetics of developmental dyslexia

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[Zeitschriftenartikel]

Scerri, Thomas S.; Schulte-Körne, Gerd

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Abstract	Developmental dyslexia is a highly heritable disorder with a prevalence of at least 5% in school-aged children. Linkage studies have identified numerous loci throughout the genome that are likely to harbour candidate dyslexia susceptibility genes. Association studies and the refinement of chromosomal translocation break points in individuals with dyslexia have resulted in the discovery of candidate genes at some of these loci. A key function of many of these genes is their involvement in neuronal migration. This complements anatomical abnormalities discovered in dyslexic brains, such as ectopias, that may be the result of irregular neuronal migration.
Klassifikation	Allgemeine Psychologie; psychische Störungen, Behandlung und Prävention
Freie Schlagwörter	Developmental dyslexia; Genetics; Reading; Spelling
Sprache Dokument	Englisch
Publikationsjahr	2009
Seitenangabe	S. 179-197
Zeitschriftentitel	European Child & Adolescent Psychiatry, 19 (2009) 3
DOI	http://dx.doi.org/10.1007/s00787-009-0081-0
Status	Postprint; begutachtet (peer reviewed)
Lizenz	PEER Licence Agreement (applicable only to documents from PEER project)