Bookmark and Share

Course of intelligence deficits in early onset, first episode schizophrenia: a controlled, 5-year longitudinal study

[journal article]

Moellegaard Jepsen, Jens Richardt; Fagerlund, Birgitte; Pagsberg, Anne Katrine; Christensen, Anne Marie R.; Hilker, Rikke W.; Nordentoft, Merete; Mortensen, Erik L.

fulltextDownloadDownload full text

(261 KByte)

Citation Suggestion

Please use the following Persistent Identifier (PID) to cite this document:http://nbn-resolving.de/urn:nbn:de:0168-ssoar-202962

Further Details
Abstract Only few prospective longitudinal studies have assessed the course of intelligence deficits in early onset schizophrenia (EOS), and these have used different age appropriate versions of Wechsler Intelligence Scales and age appropriate norms. The post-psychotic development of intelligence in EOS has predominantly been characterized as relatively stable in these studies. However, comparisons of IQs from different test versions based on the different norms may not permit unequivocal interpretations. The objective of the current study was to compare the development of intelligence in EOS patients (N = 10) from their first psychotic episode to 5 years of post onset with that of healthy controls (N = 35) and patients who at baseline had been diagnosed with other non-affective psychoses (N = 8). The same version of a Wechsler Intelligence Scale was administered at both baseline and follow-up assessments, and the same norms were used to derive IQs at baseline and follow-up. Significantly smaller change in mean full scale intelligence quotient (FSIQ) was found in diagnostically stable EOS patients compared with healthy controls during the follow-up period. However, no statistically significant difference in mean FSIQ change was observed between patients with EOS and patients with other non-affective psychoses, although this result must be interpreted with caution due to the small sample sizes. The results suggest abnormally slow acquisition of new intellectual information and skills in EOS patients during the first 5 years after full clinical presentation.
Classification Psychological Disorders, Mental Health Treatment and Prevention
Free Keywords Intelligence; IQ; Longitudinal; Adolescent; Schizophrenia; Early onset psychosis
Document language English
Publication Year 2009
Page/Pages p. 341-351
Journal European Child & Adolescent Psychiatry, 19 (2009) 4
DOI http://dx.doi.org/10.1007/s00787-009-0053-4
Status Postprint; peer reviewed
Licence PEER Licence Agreement (applicable only to documents from PEER project)