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A randomised controlled trial into the effects of food on ADHD

[journal article]

Pelsser, Lidy M. J.; Frankena, Klaas; Toorman, Jan; Savelkoul, Huub F. J.; Pereira, Rob Rodrigues; Buitelaar, Jan K.

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Please use the following Persistent Identifier (PID) to cite this document:http://nbn-resolving.de/urn:nbn:de:0168-ssoar-123142

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Abstract The aim of this study is to assess the efficacy of a restricted elimination diet in reducing symptoms in an unselected group of children with Attention deficit/hyperactivity disorder (ADHD). Dietary studies have already shown evidence of efficacy in selected subgroups. Twenty-seven children (mean age 6.2) who all met the DSM-IV criteria for ADHD, were assigned randomly to either an intervention group (15/27) or a waiting-list control group (12/27). Primary endpoint was the clinical response, i.e. a decrease in the symptom scores by 50% or more, at week 9 based on parent and teacher ratings on the abbreviated ten-item Conners Scale and the ADHD-DSM-IV Rating Scale. The intention-to-treat analysis showed that the number of clinical responders in the intervention group was significantly larger than that in the control group [parent ratings 11/15 (73%) versus 0/12 (0%); teacher ratings, 7/10 (70%) versus 0/7 (0%)]. The Number of ADHD criteria on the ADHD Rating Scale showed an effect size of 2.1 (cohen’s d) and a scale reduction of 69.4%. Comorbid symptoms of oppositional defiant disorder also showed a significantly greater decrease in the intervention group than it did in the control group (cohens’s d 1.1, scale reduction 45.3%). A strictly supervised elimination diet may be a valuable instrument in testing young children with ADHD on whether dietary factors may contribute to the manifestation of the disorder and may have a beneficial effect on the children’s behaviour.
Classification Psychological Disorders, Mental Health Treatment and Prevention
Free Keywords ADHD; few foods diet; elimination diet; children; randomised controlled trial
Document language English
Publication Year 2008
Page/Pages p. 12-19
Journal European Child & Adolescent Psychiatry, 18 (2008) 1
DOI http://dx.doi.org/10.1007/s00787-008-0695-7
Status Published Version; peer reviewed
Licence PEER Licence Agreement (applicable only to documents from PEER project)